5′
发布时间:2019-03-12 来源:文档文库
小
中
大
字号:
5′
作者:李顺君,黄文方,饶绍琴
【摘要】 目的 检测各型肝胆疾病、骨骼疾病患者血清5′-核苷酸酶 (5′-NT,谷丙转氨酶(ALT和γ-谷氨酰转肽酶,碱性磷酸酶 (ALP 酶活性的变化,观察在肝胆疾病和骨骼疾病中的临床意义,同时与正常健康者作对照。方法 用法国Biomerieux公司 (5′-NT诊断试剂盒测定血清5′-NT酶活性,同时测定患者血清谷丙转氨酶(ALT和γ-谷氨酰转肽酶,碱性磷酸酶 (ALP 酶活性的变化。结果 发现在肝胆疾病和骨骼疾病时,血清5′-NT酶活性升高,尤其是急性黄疸型肝炎、肝癌、胆道疾病患者血清5′-NT酶活性差异有非常显着性时,随病情好转,血清5′-NT酶活性有所降低。结论 (1 血清5′-核苷酸酶(5′-NT 酶活性测定对诊断肝胆疾病、骨骼疾病具有重要价值。(2联合检测血清5′-核苷酸酶 (5′-NT,谷丙转氨酶(ALT和γ-谷氨酰转肽酶,碱性磷
酸酶 (ALP 酶活性的检测有助于鉴别诊断肝脏疾病、胆道疾病和骨骼疾病。
【关键词】 5′-核苷酸酶;谷丙转氨酶;γ-谷氨酰转肽酶;碱性磷酸酶 ;肝胆疾病;骨髓疾病
【Abstract】 Objective To study the serum active enzymatic of 5′-NT and ALT,γ-GGT and ALP and in hepatic and gall diseases,osteal diseases,compared with the normal period as the control group. Methods The serum active enzymatic of 5′-NT were examined using Biomerieux sa Francais Enzyline 5′-NT kit, together with ALT,γ-GGT and ALP .Results It showed that the serum active enzymatic of 5′-NT in hepatic and gall diseases,osteal diseases levels were increase, especially the more significant increase of the serum active enzymatic of 5′-NT in level appeared in the
patients with hepatic and gall diseases,osteal diseases .It showed that the application of 5′-NT in acute hepatitis, live cancer and osteal diseases were significantly higher than that of controls. The serum active enzymatic of 5′-NT may be useful in diagnosis and differentiation of some hepatocirrhosis and liver the diseases getting better ,the application of 5′-NT gradually (1 The serum active enzymatic of 5′-NT level was